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The presence of foreign bodymaterial leads to a locally impaired host defense (see Chapter 8) [3]. Collections of such cells are sometimes calledprimitive fat organs.

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Deep-lying cells in hair roots move forwardthrough the hair follicles, or shafts, that hold the hair fiber. The wall of the sinuses allows lymph to percolate freelyinto the superficial and deep cortex, allowing lymphocytes to engage inimmunosurveillance.The lymphocytes that enterthe tissue next migratebackto the sinusesand leavethe lymph node with the flow ofthe lymph.Lymphocytes that migrate to the lymph node from the blood (bluearrows) enter the deep cortexvia high endothelial venules {HEVs) and alsomigrate to the superficial cortex. Unfortunately, quantitativeHIV RNA polymerase chain reaction (PCR) performed onCSF is not sufficiently sensitive or specific to serve as aguide. Two of these three core featureswere required for a diagnosis of probable DLB.

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The uptake of vapor is determined by thealveolar ventilation (Q ), cardiac output (Q ), blood:air partition coefficient, and the concentration gradient between arterial and venouspulmonary blood (C and C ). The rest had a variety of serious complaints including can-cer, cardiovascular disease, arthritis, deafness and respiratory problems

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