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Variable shades of pink material represent collagenfibers deposited in athicktunica intima, which contains advanced ath-eromatous plaque with visible calcifications {darkpink-orange color)and accumulation of extracellular lipids (cholesterol clefts).The lightpink color surrounding the lumen of the vessel represents the mostrecent deposition ofthe pathological material. Symptoms of bipolar disorder can encompassa wide range of characteristics evident when one experiences a manic episode,depending on the severity and duration of the symptoms

Symptoms of bipolar disorder can encompassa wide range of characteristics evident when one experiences a manic episode,depending on the severity and duration of the symptoms.

Insome areas, the epithelium appears thick (arrowhead) and, based on thedisposition ofthe nuclei, would seem to be multilayered.